Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.
BACKGROUND: Clostridium difficile is a major cause of nosocomial diarrhea, with 30-day mortality reaching 30%. The cell surface comprises a paracrystalline proteinaceous S-layer encoded by the slpA gene within the cell wall protein (cwp) gene cluster. Our purpose was to understand the diversity and...
Κύριοι συγγραφείς: | Dingle, K, Didelot, X, Ansari, M, Eyre, D, Vaughan, A, Griffiths, D, Ip, C, Batty, E, Golubchik, T, Bowden, R, Jolley, K, Hood, D, Fawley, W, Walker, A, Peto, T, Wilcox, M, Crook, D |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Evolutionary history of the Clostridium difficile pathogenicity locus.
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Clinical Clostridium difficile: clonality and pathogenicity locus diversity.
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Microevolutionary analysis of Clostridium difficile genomes to investigate transmission.
ανά: Didelot, X, κ.ά.
Έκδοση: (2012) -
Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
ανά: Didelot, X, κ.ά.
Έκδοση: (2012) -
Multilocus sequence typing of Clostridium difficile.
ανά: Griffiths, D, κ.ά.
Έκδοση: (2010)