Toxin import through the antibiotic efflux channel TolC

Bacteria often secrete diffusible protein toxins (bacteriocins) to kill bystander cells during interbacterial competition. Here, we use biochemical, biophysical and structural analyses to show how a bacteriocin exploits TolC, a major outer-membrane antibiotic efflux channel in Gram-negative bacteria...

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Bibliographic Details
Main Authors: Housden, NG, Webby, MN, Lowe, ED, El-Baba, TJ, Kaminska, R, Robinson, CV, Kleanthous, C, Redfield, C
Format: Journal article
Language:English
Published: Springer Nature 2021