EFFECTS OF CATIONIC MODIFICATION ON SUPERFICIAL BINDING AND INTRACELLULAR CA-45 UPTAKE BY DECAPSULATED OB/OB MOUSE PANCREATIC-ISLETS

Decapsulated ob/ob mouse islets were used to examine the effects of monovalent and divalent cations on 45Ca uptake and binding as discriminated by La3+-wash technique. At 3 mM glucose (1.28 mM Ca2+), intracellular 45Ca uptake was increased 1.9-4.5-fold by omission of 125 mM Na+, 1.5-fold by omission...

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Bibliographic Details
Main Authors: Flatt, P, Rorsman, P, Swanstonflatt, S
Format: Journal article
Language:English
Published: 1987