PKA microdomain organisation and cAMP handling in healthy and dystrophic muscle in vivo.
Signalling through protein kinase A (PKA) triggers a multitude of intracellular effects in response to a variety of extracellular stimuli. To guarantee signal specificity, different PKA isoforms are compartmentalised by Akinase anchoring proteins (AKAPs) into functional microdomains. By using geneti...
Hauptverfasser: | , , , , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2009
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