PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells
Single-cell RNA-seq quantifies biological heterogeneity across both discrete cell types and continuous cell transitions. Partition-based graph abstraction (PAGA) provides an interpretable graph-like map of the arising data manifold, based on estimating connectivity of manifold partitions (https://gi...
Prif Awduron: | Wolf, FA, Hamey, FK, Plass, M, Solana, J, Dahlin, JS, Göttgens, B, Rajewsky, N, Simon, L, Theis, FJ |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
BioMed Central
2019
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Eitemau Tebyg
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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells
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