PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

Single-cell RNA-seq quantifies biological heterogeneity across both discrete cell types and continuous cell transitions. Partition-based graph abstraction (PAGA) provides an interpretable graph-like map of the arising data manifold, based on estimating connectivity of manifold partitions (https://gi...

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מידע ביבליוגרפי
Main Authors: Wolf, FA, Hamey, FK, Plass, M, Solana, J, Dahlin, JS, Göttgens, B, Rajewsky, N, Simon, L, Theis, FJ
פורמט: Journal article
שפה:English
יצא לאור: BioMed Central 2019

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