Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation.

A goal of molecular genetics is to understand the relationship between basic nuclear processes, epigenetic changes and the numerous proteins that orchestrate these effects. One such protein, ATRX, contains a highly conserved plant homeodomain (PHD)-like domain, present in many chromatin-associated p...

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Bibliographic Details
Main Authors: Gibbons, R, McDowell, T, Raman, S, O'Rourke, D, Garrick, D, Ayyub, H, Higgs, D
Format: Journal article
Language:English
Published: 2000