Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas in vivo.

OBJECTIVE: To develop an image processing-based method to quantify the rate of extravasation of fluorescent contrast agents from tumor microvessels, and to investigate the effect of the tumor vascular disrupting agent combretastatin A-4-P (CA-4-P) on apparent tumor vascular permeability to 40 kDa fl...

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Bibliographic Details
Main Authors: Reyes-Aldasoro, C, Wilson, I, Prise, V, Barber, P, Ameer-Beg, M, Vojnovic, B, Cunningham, V, Tozer, G
Format: Journal article
Language:English
Published: 2008