HLA-DR/DQ haplotype in rheumatoid arthritis: novel allelic associations in UK Caucasians.

OBJECTIVE: To elucidate the relative importance of the HLA-DR and HLA-DQ loci in conferring genetic predisposition to rheumatoid arthritis (RA). METHODS: HLA-DRB1 and HLA-DQB1 alleles were typed in a set of 685 patients with RA using sequence-specific polymerase chain reaction. Allele and phenotype...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Milicic, A, Lee, D, Brown, M, Darke, C, Wordsworth, B
Format: Journal article
Sprache:English
Veröffentlicht: 2002