HLA-DR/DQ haplotype in rheumatoid arthritis: novel allelic associations in UK Caucasians.

OBJECTIVE: To elucidate the relative importance of the HLA-DR and HLA-DQ loci in conferring genetic predisposition to rheumatoid arthritis (RA). METHODS: HLA-DRB1 and HLA-DQB1 alleles were typed in a set of 685 patients with RA using sequence-specific polymerase chain reaction. Allele and phenotype...

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Main Authors: Milicic, A, Lee, D, Brown, M, Darke, C, Wordsworth, B
Formato: Journal article
Idioma:English
Publicado em: 2002