Direct measurement of T cell subset kinetics in vivo in elderly men and women.

The age-associated decline in immunocompetence is paralleled by changes in the proportions of PBL subpopulations. In turn, the size and composition of the peripheral lymphocyte pool is determined by input from the thymus and bone marrow and by the balance of proliferation and death in each lymphocyt...

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Bibliographic Details
Main Authors: Wallace, D, Zhang, Y, Ghattas, H, Worth, A, Irvine, A, Bennett, A, Griffin, G, Beverley, P, Tough, D, Macallan, D
Format: Journal article
Language:English
Published: 2004