Rational optimization and imaging in vivo of a genetically encoded optical voltage reporter.

The hybrid voltage sensor (hVOS) combines membrane-targeted green fluorescent protein and the hydrophobic anion dipicrylamine (DPA) to provide a promising tool for optical recording of electrical activity from genetically defined populations of neurons. However, large fluorescence signals are obtain...

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Detalhes bibliográficos
Principais autores: Sjulson, L, Miesenböck, G
Formato: Journal article
Idioma:English
Publicado em: 2008