Epistatic interactions between ancestral genotype and beneficial mutations shape evolvability in Pseudomonas aeruginosa.

The idea that interactions between mutations influence adaptation by driving populations to low and high fitness peaks on adaptive landscapes is deeply ingrained in evolutionary theory. Here we investigate the impact of epistasis on evolvability by challenging populations of two Pseudomonas aerugino...

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Autors principals: Gifford, D, Toll-Riera, M, MacLean, R
Format: Journal article
Idioma:English
Publicat: Wiley 2016