5′-O-Methyldioncophylline D, a 7,8′-coupled naphthylisoquinoline alkaloid from callus cultures of Triphyophyllum peltatum, and its biosynthesis from a late-stage tetrahydroisoquinoline precursor
The natural tetrahydroisoquinoline phylline (4) was synthesized in a specifically [1,1′-13C2]-labeled form, and fed to callus cultures of Triphyophyllum peltatum. Its incorporation into naphthylisoquinoline alkaloids, among them habropetaline A (8) (as evidenced by1H,13C NMR, and 2D INADEQUATE exper...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Elsevier
2016
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