Modeling the mutation and reversal of engineered underdominance gene drives

A range of gene drive systems have been proposed that are predicted to increase their frequency and that of associated desirable genetic material even if they confer a fitness cost on individuals carrying them. Engineered underdominance (UD) is such a system and, in one version, is based on the intr...

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Bibliographic Details
Main Authors: Edgington, M, Alphey, L
Format: Journal article
Language:English
Published: Elsevier 2019