miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense.

Radiotherapy (RT) is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer (BC) via its regulation of genes involved in m...

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Détails bibliographiques
Auteurs principaux:	Pajic, M, Froio, D, Daly, S, Doculara, L, Millar, E, Graham, PH, Drury, A, Steinmann, A, de Bock, CE, Boulghourjian, A, Zaratzian, A, Carroll, S, Toohey, J, O'Toole, SA, Harris, AL, Buffa, FM, Gee, HE, Hollway, GE, Molloy, TJ
Format:	Journal article
Langue:	English
Publié:	American Association for Cancer Research 2017

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense.

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