Integrative proximal-ubiquitomics profiling for deubiquitinase and E3 ligase substrate discovery applied to USP30
Increasing interest in deubiquitinases (DUBs) and ubiquitin E3 ligases as drug targets to modulate critical molecular pathways in disease is driven by the discovery of specific cellular roles of these enzymes. Key to this is the identification of DUB or E3 ligase substrates. While global cellular ub...
| Autores principales: | , , , , , |
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| Formato: | Internet publication |
| Lenguaje: | English |
| Publicado: |
2024
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