Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the preferential loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction is increasingly appreciated as a key determinant of dopaminergic neuronal susceptibility in PD and is a feature...

Полное описание

Библиографические подробности
Главные авторы: Ryan, B, Hoek, S, Fon, E, Wade-Martins, R
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2015