Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.

Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.

OBJECTIVES: Major histocompatibility complex class I (MHC-I) proteins exist at the cell surface in antigen presenting forms and as beta2m-independent free heavy chains (FHCs). FHCs have been implicated in spondyloarthritis, but little is known about their expression in healthy individuals. We studie...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Raine, T, Brown, D, Bowness, P, Hill Gaston, J, Moffett, A, Trowsdale, J, Allen, R
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2006

Antzeko izenburuak

CELL SURFACE EXPRESSION OF HLA B27 HEAVY CHAINS AND SPECIFIC RECOGNITION BY IMMUNE RECEPTORS, POSSIBLE ROLE IN SPONDYLOARTHROPATHY
nork: Kollnberger, S, et al.
Argitaratua: (2002)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
nork: Rysnik, O, et al.
Argitaratua: (2013)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
nork: Rysnik, O, et al.
Argitaratua: (2013)

Genotyping HLA-B27 in spondyloarthropathies.
nork: Brown, M, et al.
Argitaratua: (1998)

Role of HLA genes in familial spondyloarthropathy.
nork: Brown, M, et al.
Argitaratua: (2002)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
nork: Rysnik, O, et al.
Argitaratua: (2012)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
nork: Rysnik, O, et al.
Argitaratua: (2012)

Genes in the spondyloarthropathies.
nork: Wordsworth, P
Argitaratua: (1998)

Ochronotic Spondyloarthropathy
nork: Upasana Ranga, et al.
Argitaratua: (2013-02-01)

Espondilartropatias Spondyloarthropathies
nork: Valderílio Feijó Azevedo, et al.
Argitaratua: (2004-08-01)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
nork: Bowness, P, et al.
Argitaratua: (2003)

Predisposing factors to spondyloarthropathies.
nork: Brown, M, et al.
Argitaratua: (1997)

THE ASSOCIATION OF ERAP2 GENE POLYMORPHISMS WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN HLA-B27 NEGATIVE ROMANIANS
nork: Laura Ioana Cherciu, et al.
Argitaratua: (2016-06-01)

Functional expression of HLA-DP genes transfected into mouse fibroblasts.
nork: Austin, P, et al.
Argitaratua: (1985)

Uveitis in spondyloarthropathies: Current concepts
nork: Krati Chauhan
Argitaratua: (2020-01-01)

Gender and Spondyloarthropathy-Associated Uveitis
nork: Wendy M. Smith
Argitaratua: (2013-01-01)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
nork: Kollnberger, S, et al.
Argitaratua: (2004)

Interactions between HLA-G and HLA-E in physiological and pathological conditions
nork: Fabio eMorandi, et al.
Argitaratua: (2014-08-01)

Position 97 of HLA-B, a residue implicated in pathogenesis of ankylosing spondylitis, plays a key role in cell surface free heavy chain expression
nork: Chen, L, et al.
Argitaratua: (2016)

HLA B27 can form heavy chain homodimers in vivo and in vivo, possible role of cys 67.
nork: Bowness, P, et al.
Argitaratua: (1998)

Hypophosphataemia: An under-recognized cause of spondyloarthropathy
nork: Wordsworth, P, et al.
Argitaratua: (2008)

ABZYME ACTIVITY OF POLYCLONAL IMMUNOGLOBULINS IN SPONDYLOARTHROPATHIES
nork: E. V. Kunder
Argitaratua: (2014-07-01)

Ultrasonography in the evaluation of peripheral enthesitis in spondyloarthropathy
nork: Sumeet Agrawal, et al.
Argitaratua: (2017-01-01)

Brucellosis sacroiliitis masquerading as inflammatory spondyloarthropathy
nork: Alok Gupta, et al.
Argitaratua: (2022-01-01)

Position 97 (P97) of HLA-B, implicated in Ankylosing Spondylitis pathogenesis, affects cell surface free heavy chain expression: Evidence of interaction with beta 2 microglobulin
nork: Chen, L, et al.
Argitaratua: (2016)

Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies.
nork: Mear, J, et al.
Argitaratua: (1999)

A study of clinical, radiological features and HLA-B27 serology of axial spondyloarthropathy with comparison of radiographic and non-radiographic disease
nork: Manaswini Edara, et al.
Argitaratua: (2022-01-01)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
nork: McHugh, K, et al.
Argitaratua: (2008)

JAK1 selective inhibitors for the treatment of spondyloarthropathies
nork: White, JPE, et al.
Argitaratua: (2021)

Physical activity as part of therapy of spondyloarthropathy - review
nork: Karolina Mikołajczak, et al.
Argitaratua: (2025-03-01)

The association of anti-CD74 antibody with spondyloarthropathies
nork: Seda Çolak, et al.
Argitaratua: (2021-10-01)

Similarities and Differences Between Juvenile and Adult Spondyloarthropathies
nork: Corinne Fisher, et al.
Argitaratua: (2021-05-01)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
nork: Bowness, P, et al.
Argitaratua: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
nork: Bowness, P, et al.
Argitaratua: (2010)

Dimers are forever. Expression and recognition of abnormal HLA-B27 in spondylo arthritis
nork: Bowness, P, et al.
Argitaratua: (2005)

A PHYSICAL MAP OF THE HLA COMPLEX
nork: Ziegler, A, et al.
Argitaratua: (1987)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
nork: Giles, J, et al.
Argitaratua: (2008)

Factors determining the cell surface expression of a novel HLA-B27 epitope
nork: McHugh, K, et al.
Argitaratua: (2010)

Influence of HLA-C expression level on HIV control.
nork: Apps, R, et al.
Argitaratua: (2013)

Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy
nork: Gravenor Michael B, et al.
Argitaratua: (2008-01-01)