The role of LKB1 (STK11) in non-small cell lung cancer

<p>LKB1 is the second most commonly altered tumour suppressor gene in lung adenocarcinoma, the most prevalent form of lung cancer. LKB1 is a "master kinase" that has been shown to phosphorylate up to 13 downstream targets. We hypothesised that LKB1 loss is associated with an increase...

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Bibliographic Details
Main Author: Cahill, F
Other Authors: Ryan, A
Format: Thesis
Language:English
Published: 2017
Subjects: