The role of LKB1 (STK11) in non-small cell lung cancer
<p>LKB1 is the second most commonly altered tumour suppressor gene in lung adenocarcinoma, the most prevalent form of lung cancer. LKB1 is a "master kinase" that has been shown to phosphorylate up to 13 downstream targets. We hypothesised that LKB1 loss is associated with an increase...
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格式: | Thesis |
语言: | English |
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2017
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