Perspectives on the genetic associations of ankylosing spondylitis

Ankylosing spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex polygenic aetiology. Genome-wide association studies have identified more than 100 loci, including some involved in antigen presentation (HLA-B27, ERAP1, and ERAP2), some in Th17 responses (IL6R, IL23R, TYK2...

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Bibliografische gegevens
Hoofdauteurs: Wordsworth, BP, Cohen, CJ, Davidson, C, Vecellio, M
Formaat: Journal article
Taal:English
Gepubliceerd in: Frontiers Media 2021