BRCA2, but not BRCA1, mutations account for familial ovarian cancer in Iceland: a population-based study.
A single founder mutation in each of the BRCA genes has been identified in Iceland. The frequency of the BRCA1 G5193A and BRCA2 999del5 mutations in all ovarian cancer patients diagnosed over the period 1991-2000 was determined. Mutation status was correlated with family history, tumour morphology a...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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