Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein

Preventing the protein-protein interaction of the cellular chromatin binding protein Lens Epithelium- Derived Growth Factor (LEDGF) and human immunodeficiency virus (HIV) integrase is an important possible strategy for anti-viral treatment for AIDS. We have used Intracellular Antibody Capture techno...

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Bibliographic Details
Main Authors: Bao, L, Hannon, C, Cruz-Mignoni, A, Ptchelkine, D, Sun, M, Miller, A, Bunjobpol, W, Quevedo, C, Derveni, M, Chambers, J, Simmons, A, Phillips, S, Rabbitts, T
Format: Journal article
Published: Nature Publishing Group 2017