Getting through anaphase: splitting the sisters and beyond.
Sister-chromatid cohesion, thought to be primarily mediated by the cohesin complex, is essential for chromosome segregation. The forces holding the two sisters resist the tendency of microtubules to prematurely pull sister DNAs apart and thereby prevent random segregation of the genome during mitosi...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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