Cyclin D1 (CCND1) genotype is associated with tumour grade in sporadic pituitary adenomas.

The cyclin D1 (CCND1) gene contains a frequent A/G polymorphism within the splice donor region of exon 4/intron 4. CCND1 genotype is associated with clinical outcome in a number of malignancies although prognostic significance varies with tumour type. We examined CCND1 allele frequencies and genotyp...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Simpson, D, Fryer, A, Grossman, AB, Wass, J, Pfeifer, M, Kros, J, Clayton, R, Farrell, W
Format: Journal article
Sprache:English
Veröffentlicht: 2001