Control of cross-presentation during dendritic cell maturation.

The initiation of most cytotoxic immune responses requires MHC class I-restricted presentation of internalized antigens to CD8(+) T lymphocytes, a process called cross-presentation. In dendritic cells (DC), the only antigen-presenting cells that activate naive T cells, cross-presentation is particul...

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Bibliographic Details
Main Authors: Gil-Torregrosa, B, Lennon-Duménil, A, Kessler, B, Guermonprez, P, Ploegh, H, Fruci, D, van Endert, P, Amigorena, S
Format: Journal article
Language:English
Published: 2004