Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity

Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the [Formula: see text] ratio. Because of the ceiling effect in oxyhaemoglobin...

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Bibliographic Details
Main Authors: Swets, MC, Kerr, S, Scott-Brown, J, Brown, AB, Gupta, R, Millar, JE, Spata, E, McCurrach, F, Bretherick, AD, Docherty, A, Harrison, D, Rowan, K, Young, N, Groeneveld, GH, Dunning, J, Nguyen-Van-Tam, JS, Openshaw, P, Horby, PW, Harrison, E, Staplin, N, Semple, MG, Lone, N, Baillie, JK
Other Authors: ISARIC4C Investigators
Format: Journal article
Language:English
Published: Springer Nature 2023