A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE)

Background Enadenotucirev is a chimeric adenovirus with demonstrated preclinical tumor-selective cytotoxicity and a short half-life. Further clinical mechanism of action data showed that enadenotucirev can gain access to and replicate within different types of epithelial tumors. This phase 1 dose es...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Machiels, JP, Salazar, R, Rottey, S, Duran, I, Dirix, L, Geboes, K, Wilkinson-Blanc, C, Pover, G, Alvis, S, Champion, B, Fisher, K, McElwaine-Johnn, H, Beadle, J, Calvo, E
Μορφή: Journal article
Γλώσσα:English
Έκδοση: BMJ Publishing Group 2019