The design and development of a multi-hbv antigen encoded in chimpanzee adenoviral and modified vaccinia ankara viral vectors; a novel therapeutic vaccine strategy against HBV

Chronic hepatitis B virus (HBV) infection affects 257 million people globally. Current therapies suppress HBV but viral rebound occurs on cessation of therapy; novel therapeutic strategies are urgently required. To develop a therapeutic HBV vaccine that can induce high magnitude T cells to all major...

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Bibliographic Details
Main Authors: Chinnakannan, SK, Cargill, TN, Donnison, TA, Ansari, MA, Sebastian, S, Lee, LN, Hutchings, C, Klenerman, P, Maini, MK, Evans, T, Barnes, E
Format: Journal article
Language:English
Published: MDPI 2020