GTP cyclohydrolase as a novel mechanism for tumour growth

Background Improvement of patient with cancer outcome can be achieved by identifying novel mechanisms that underlie cancer pathogenesis. GTP cyclohydrolase (GTPCH) is the rate-limiting enzyme for neopterin and tetrahydrobiopterin (BH4) synthesis. Elevated neopterin in patients associates strongly wi...

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Bibliographic Details
Main Authors: Chen, L, Zhang, W, Leek, R, Buffa, F, Fokas, E, Harris, A, Cai, S
Format: Conference item
Published: NCRI 2015