Metformin maintains intrahepatic triglyceride content through increased hepatic de novo lipogenesis

<p><strong>Objective:</strong> Metformin is a first-line pharmacotherapy in the treatment of type 2 diabetes, a condition closely associated with NAFLD. Although metformin promotes weight loss and improves insulin sensitivity, its effect on intrahepatic triglyceride (IHTG) remains...

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Main Authors: Green, CJ, Marjot, T, Walsby-Tickle, J, Charlton, C, Cornfield, T, Westcott, F, Pinnick, KE, Moolla, A, Hazlehurst, JM, McCullagh, J, Tomlinson, JW, Hodson, L
Format: Journal article
Language:English
Published: Bioscientifica 2022