The NUCKS1-SKP2-p21/p27 axis controls S phase entry
Efficient entry into S phase of the cell cycle is necessary for embryonic development and tissue homoeostasis. However, unscheduled S phase entry triggers DNA damage and promotes oncogenesis, underlining the requirement for strict control. Here, we identify the NUCKS1-SKP2-p21/p27 axis as a checkpoi...
Main Authors: | Hume, S, Grou, CP, Lascaux, P, D'Angiolella, V, Legrand, AJ, Ramadan, K, Dianov, GL |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2021
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