Investigating acquired temozolomide resistance in adult glioblastoma
<p>Glioblastoma is the most aggressive primary malignant brain tumour in adults with very poor prognosis. Current management includes surgery, radiotherapy and temozolomide (TMZ), which causes three types of DNA methylation: O6-methylguanine (O<sup>6</sup>-meG), N7-methylguanine an...
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| Format: | Thesis |
| Language: | English |
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2020
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