Investigating acquired temozolomide resistance in adult glioblastoma
<p>Glioblastoma is the most aggressive primary malignant brain tumour in adults with very poor prognosis. Current management includes surgery, radiotherapy and temozolomide (TMZ), which causes three types of DNA methylation: O6-methylguanine (O<sup>6</sup>-meG), N7-methylguanine an...
Hlavní autor: | |
---|---|
Další autoři: | |
Médium: | Diplomová práce |
Jazyk: | English |
Vydáno: |
2020
|
Témata: |