Investigating acquired temozolomide resistance in adult glioblastoma

<p>Glioblastoma is the most aggressive primary malignant brain tumour in adults with very poor prognosis. Current management includes surgery, radiotherapy and temozolomide (TMZ), which causes three types of DNA methylation: O6-methylguanine (O<sup>6</sup>-meG), N7-methylguanine an...

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書目詳細資料
主要作者: Wong, ZY
其他作者: Macaulay, V
格式: Thesis
語言:English
出版: 2020
主題: