Facilitation by intracellular carbonic anhydrase of Na-HCO co-transport but not Na/H exchange activity in the mammalian ventricular myocyte

Carbonic anhydrase enzymes (CAs) catalyse the reversible hydration of CO to H and HCO ions. This catalysis is proposed to be harnessed by acid/base transporters, to facilitate their transmembrane flux activity, either through direct protein-protein binding (a 'transport metabolon') or loc...

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Библиографические подробности
Главные авторы: Villafuerte, F, Swietach, P, Youm, J, Ford, K, Cardenas, R, Cobden, P, Rohling, M, Vaughan-Jones, R, Supuran, C
Формат: Journal article
Опубликовано: 2014