The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.

The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.

OBJECTIVES: HLA-B*27:05 is associated with AS whereas HLA-B*27:09 is not associated. We hypothesized that different interactions with KIR immune receptors could contribute to the difference in disease association between HLA-B*27:05 and HLAB*27:09. Thus, the objective of this study was to compare th...

Полное описание

Библиографические подробности
Главные авторы: Cauli, A, Shaw, J, Giles, J, Hatano, H, Rysnik, O, Payeli, S, McHugh, K, Dessole, G, Porru, G, Desogus, E, Fiedler, S, Hölper, S, Carette, A, Blanco-Gelaz, M, Vacca, A, Piga, M, Ibba, V, Garau, P, La Nasa, G, López-Larrea, C, Mathieu, A, Renner, C, Bowness, P, Kollnberger, S
Формат: Journal article
Язык:English
Опубликовано: Oxford University Press 2013

Схожие документы