The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.

The arthritis-associated HLA-B27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B27:09.

OBJECTIVES: HLA-B*27:05 is associated with AS whereas HLA-B*27:09 is not associated. We hypothesized that different interactions with KIR immune receptors could contribute to the difference in disease association between HLA-B*27:05 and HLAB*27:09. Thus, the objective of this study was to compare th...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Cauli, A, Shaw, J, Giles, J, Hatano, H, Rysnik, O, Payeli, S, McHugh, K, Dessole, G, Porru, G, Desogus, E, Fiedler, S, Hölper, S, Carette, A, Blanco-Gelaz, M, Vacca, A, Piga, M, Ibba, V, Garau, P, La Nasa, G, López-Larrea, C, Mathieu, A, Renner, C, Bowness, P, Kollnberger, S
Format:	Journal article
Sprog:	English
Udgivet:	Oxford University Press 2013

Lignende værker

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
af: Wong-Baeza, I, et al.
Udgivet: (2011)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
af: Giles, J, et al.
Udgivet: (2010)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
af: Rysnik, O, et al.
Udgivet: (2012)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
af: McHugh, K, et al.
Udgivet: (2014)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
af: Rysnik, O, et al.
Udgivet: (2012)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
af: Kollnberger, S, et al.
Udgivet: (2007)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
af: Shaw, J, et al.
Udgivet: (2013)

HLA-B27
af: Bowness, P
Udgivet: (2015)

The role of HLA-B27 molecules in the pathogenesis of ankylosing spondylitis
af: A. Cauli, et al.
Udgivet: (2002-09-01)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
af: Rysnik, O, et al.
Udgivet: (2013)

Enhanced Expression of KIR3DL2 in Natural Killer and CD3/CD4 Positive T Cells of Ankylosing Spondylitis Patients Compared to HLA-B*2705 or B*2709 Healthy Subjects
af: Cauli, A, et al.
Udgivet: (2011)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
af: Kollnberger, S, et al.
Udgivet: (2012)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
af: Bowness, P, et al.
Udgivet: (2003)

Functional characterisation of HLA-B27 in autoimmunity
af: Kollnberger, S, et al.
Udgivet: (2001)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats.
af: Osiris Marroquin Belaunzaran, et al.
Udgivet: (2015-01-01)

Molecular determinants for KIR3DL2 binding to HLA-B27 and other HLA-class I ligands
af: Hatano, H, et al.
Udgivet: (2013)

The role of HLA-B27 in spondyloarthritis.
af: Allen, R, et al.
Udgivet: (1999)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
af: Appel, H, et al.
Udgivet: (2004)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
af: Giles, J, et al.
Udgivet: (2008)

The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes.
af: Appel, H, et al.
Udgivet: (2004)

Identification and characterisation of cell surface HLA-B27 homodimers
af: Bird, L, et al.
Udgivet: (2002)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
af: Rysnik, O, et al.
Udgivet: (2013)

HLA-B27 and KIR3DL2 Interactions Promote The Differentiation and Survival Of Proinflammatory T Cells In Spondyloarthritis
af: Ridley, A, et al.
Udgivet: (2013)

Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases.
af: Kuon, W, et al.
Udgivet: (2001)

KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
af: Kollnberger, S, et al.
Udgivet: (2010)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
af: Kollnberger, S, et al.
Udgivet: (2004)

Jekyll and Hyde: the transformation of HLA-B27.
af: Edwards, J, et al.
Udgivet: (2000)

HLA class I typing by PCR: HLA-B27 and an African B27 subtype.
af: Hill, A, et al.
Udgivet: (1991)

Dimers are forever. Expression and recognition of abnormal HLA-B27 in spondylo arthritis
af: Bowness, P, et al.
Udgivet: (2005)

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue
af: Rysnik, O, et al.
Udgivet: (2016)

KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
af: Kollnberger, S, et al.
Udgivet: (2010)

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis.
af: Payeli, S, et al.
Udgivet: (2012)

The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of spondyloarthritis
af: Kollnberger, S, et al.
Udgivet: (2007)

KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis.
af: Wong-Baeza, I, et al.
Udgivet: (2013)

KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis.
af: Wong-Baeza, I, et al.
Udgivet: (2013)

The expression patterns of non-classical and classical forms of HLA-B27 in spondyloarthritis
af: Rysnik, O
Udgivet: (2015)

HLA-B27: natural function and pathogenic role in spondyloarthritis.
af: McMichael, A, et al.
Udgivet: (2002)

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
af: Bowness, P, et al.
Udgivet: (2011)