MyD88 adaptor-like D96N is a naturally occurring loss-of-function variant of TIRAP.

Signals elicited by TLRs following the detection of microbes are integrated and diversified by a group of four cytoplasmic adaptor molecules featuring an evolutionarily conserved Toll/IL-1R signaling domain. Single nucleotide polymorphisms (SNPs) in TLRs and their adaptor molecules have been shown t...

תיאור מלא

מידע ביבליוגרפי
Main Authors: George, J, Kubarenko, A, Rautanen, A, Mills, T, Colak, E, Kempf, T, Hill, A, Nieters, A, Weber, A
פורמט: Journal article
שפה:English
יצא לאור: 2010

פריטים דומים