Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
Allostery is a fundamental mechanism of biological regulation, in which binding of a molecule at a distant location affects the active site of a protein. Allosteric sites provide targets to fine-tune protein activity, yet we lack computational methodologies to predict them. Here we present an effici...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
Springer Nature
2016
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