Investigating radiotherapy response in a novel syngeneic model of prostate cancer

The prostate cancer (PCa) field lacks clinically relevant, syngeneic mouse models which retain the tumour microenvironment observed in PCa patients. This study establishes a cell line from prostate tumour tissue derived from the Pten-/-/trp53-/- mouse, termed DVL3 which when subcutaneously implanted...

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Bibliographic Details
Main Authors: Haughey, CM, Mukherjee, D, Steele, RE, Popple, A, Dura-Perez, L, Pickard, A, Patel, M, Jain, S, Mullan, PB, Williams, R, Oliveira, P, Buckley, NE, Honeychurch, J, S McDade, S, Illidge, T, Mills, IG, Eddie, SL
Format: Journal article
Language:English
Published: MDPI 2020