Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

There is currently a lack of effective drugs to treat people infected with SARS-CoV-2, the cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 (NSP13) has been identified as a target for anti-virals due to its high sequence conservation and essential role in viral replica...

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Bibliographic Details
Main Authors: Newman, JA, Douangamath, A, Yadzani, S, Yosaatmadja, Y, Aimon, A, Brandão-Neto, J, Dunnett, L, Gorrie-Stone, T, Skyner, R, Fearon, D, Schapira, M, von Delft, F, Gileadi, O
Format: Journal article
Language:English
Published: Springer Nature 2021