Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.
Cohesin complex acts in the formation and maintenance of sister chromatid cohesion during and after S phase. Budding yeast Scc1p/Mcd1p, an essential subunit, is cleaved and dissociates from chromosomes in anaphase, leading to sister chromatid separation. Most cohesin in higher eukaryotes, in contras...
Главные авторы: | Tomonaga, T, Nagao, K, Kawasaki, Y, Furuya, K, Murakami, A, Morishita, J, Yuasa, T, Sutani, T, Kearsey, S, Uhlmann, F, Nasmyth, K, Yanagida, M |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2000
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