Molecular classification and genetic pathways in hyperplastic polyposis syndrome.

Hyperplastic Polyposis (HPPS) is a poorly characterized syndrome that increases colorectal cancer (CRC) risk. We aimed to provide a molecular classification of HPPS. We obtained 282 tumours from 32 putative HPPS patients with >or= 10 hyperplastic polyps (HPs); some patients also had adenomas...

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Main Authors: Carvajal-Carmona, L, Howarth, K, Lockett, M, Polanco-Echeverry, G, Volikos, E, Gorman, M, Barclay, E, Martin, L, Jones, A, Saunders, B, Guenther, T, Donaldson, A, Paterson, J, Frayling, I, Novelli, MR, Phillips, R, Thomas, H, Silver, A, Atkin, W, Tomlinson, I
格式: Journal article
语言:English
出版: 2007