Chromosome 11q in sporadic colorectal carcinoma: patterns of allele loss and their significance for tumorigenesis.

AIMS: To analyse the frequency of loss of heterozygosity (allele loss, LOH) in a large sample of colorectal carcinomas using highly informative markers along chromosome 11q. METHODS: One hundred paired samples of colorectal cancer and normal tissue were genotyped at six microsatellite markers on chr...

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Bibliographic Details
Main Authors: Tomlinson, I, Bodmer, W
Format: Journal article
Language:English
Published: 1996