Chromosome 11q in sporadic colorectal carcinoma: patterns of allele loss and their significance for tumorigenesis.
AIMS: To analyse the frequency of loss of heterozygosity (allele loss, LOH) in a large sample of colorectal carcinomas using highly informative markers along chromosome 11q. METHODS: One hundred paired samples of colorectal cancer and normal tissue were genotyped at six microsatellite markers on chr...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
1996
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