Diastereoselective synthesis of P-stereogenic heterocycles via enyne ring-closing metathesis.
A range of P-containing ene-diynes suitable for desymmetrization was prepared via a two-step process starting from phosphorus oxychloride. In the presence of the Hoveyda-Grubbs II catalyst, these substrates underwent diastereoselective enyne ring-closing metathesis leading to various synthetically u...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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