Diastereoselective synthesis of P-stereogenic heterocycles via enyne ring-closing metathesis.

A range of P-containing ene-diynes suitable for desymmetrization was prepared via a two-step process starting from phosphorus oxychloride. In the presence of the Hoveyda-Grubbs II catalyst, these substrates underwent diastereoselective enyne ring-closing metathesis leading to various synthetically u...

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Bibliografische gegevens
Hoofdauteurs: Harvey, J, Giuffredi, G, Gouverneur, V
Formaat: Journal article
Taal:English
Gepubliceerd in: 2010