A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.

Enterovirus 71 (EV71) is a major agent of hand, foot and mouth disease in children that can cause severe central nervous system disease and death. No vaccine or antiviral therapy is available. High-resolution structural analysis of the mature virus and natural empty particles shows that the mature v...

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Bibliographic Details
Main Authors: Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T, Evans, G, Axford, D, Owen, R, Rowlands, D, Wang, J, Stuart, D, Fry, E, Rao, Z
Format: Journal article
Language:English
Published: 2012