Ribozymes as therapeutic tools for genetic disease.
The discovery that RNA can act as a biological catalyst, as well as a genetic molecule, indicated that there was a time when biological reactions were catalysed in the absence of protein-based enzymes. It also provided the platform to develop those catalytic RNA molecules, called ribozymes, as trans...
Main Authors: | Phylactou, L, Kilpatrick, M, Wood, M |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
1998
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Lignende værker
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Ribozyme-mediated trans-splicing of a trinucleotide repeat.
af: Phylactou, L, et al.
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The Application of Ribozymes and DNAzymes in Muscle and Brain
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Udgivet: (2010-08-01) -
Hammerhead ribozymes reduce central nervous system (CNS)-derived neuronal nitric oxide synthase messenger RNA in a human cell line.
af: Maniotis, D, et al.
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Ribozymes and siRNA for the treatment of diseases of the nervous system.
af: Wood, M, et al.
Udgivet: (2003) -
Expanding the limits of the second genetic code with ribozymes
af: Joongoo Lee, et al.
Udgivet: (2019-11-01)